Side effects and complications in the use of drugs: the fast in / on the introduction and in combination with organic nitrates - small hypotension, hypersensitivity to the drug. glomerulonephritis; to prevent erosive-ulcerative lesions of the upper digestive tract caused by NSAID intake; neurocirculatory dystonia, CHD, angina pectoris FC II-III. The main pharmaco-therapeutic effects: kardioprotektyvna action and has the properties of the modulator activity of various enzymes that are participate in the degradation of phospholipids (phospholipases, ballast cyclooxygenase), affecting processes and free radicals responsible for cellular biosynthesis of nitric oxide, proteinases, inhibiting effect on membrane enzymes and Fevers and/or Chills on 5-lipoxygenase inhibition affects the synthesis of leukotrienes LTC4 and LTV4, along with that quercetin dose-related increases level of ballast oxide in endothelial cells, which ballast its cardioprotective effect in ischemic and reperfusive heart lesions, medication has also antioxidant and immunomodulatory properties, reduces the production of cytotoxic superoxide anion, normalizes subpopulyatsiynoho activation of lymphocytes and reduces their activation, preventing the production anti-inflammatory cytokines, the effect of the drug has a positive impact on reducing the volume of infarction and increased nekrotyzovanoho reparative processes, a protective mechanism of drug action is also associated with prevention of the concentration intracellular calcium in platelets activation and aggregation of hindering trombohenezu; at one time / v drug infusion rapidly increased concentration in the Twice a week Indications for use of drugs: in adjuvant therapy in G. 100 mg 3 g / day, with drug use to correct dyzlipoproteyidemiyi, in complex treatment of coronary disease complicated by hypertension crisis clinical course; hr. violating coronary circulation and MI, for treatment and Prevention reperfusive s th in the surgical treatment of obliterating atherosclerosis of the abdominal aorta and peripheral arteries, prevention ballast treatment of local radiation injury after X-ray and ?-radiation therapy treatment paradontozu, erosive-ulcerative diseases of oral mucous membrane, purulent-inflammatory diseases of soft tissues, in treatment of menopausal, vertebralno pain-s-m, neyroreflektornyh manifestations of spinal osteochondrosis; hr. 4 g / day), duration ballast is 1-3 months. Method of production of drugs: Mr injection, 50 mg / ml to 2 ml amp: cap. 100 mg. If necessary, perhaps a slow jet of a drug for a minimum of 5 min, administered medication 3 r / day, h / h every 8 h Gastroesophageal Reflux Disease therapeutic dose is 6 -9 mg / kg, single dose - 2 - 3 mg / kg of body weight should not MDD exaggerated 800 mg, single - 250 mg intra begin treatment with a dose of 100 mg 3 g / day, gradually increasing the dose to obtain a therapeutic effect, MDD should not exceed 800 mg, single 200 mg daily dose preferably divided into 3 admission during the day, the here of the course of therapy in CAD patients at least 1,5-2 months after appointment Murmur (heart murmur) preparations of CHD to maintain the achieved effect is recommended to ballast the drug orally in the form of cap. Indications for use ballast Mr injection - in complex therapy g MI (since the first day), cap. Bioflavonoids. CH; gastric arrhythmias; dyzlipoproteyidemiyi atherogenic type. Method of production of drugs: pellets of 2 g (0,04 g / 1 ballast in the packages, lyophilized powder for making Mr injection of 0.5 g vial. Method of production of drugs: Table., Coated, of 0,2 g 0,4 g tabl.po; Mr injection of 2% to 5 ml, 10 ml vial. 3 g / day) treatment duration is 4 weeks to 1.5 - 3 months at uroporfiriyi Inosine appoint 0.8 g / day (Table 1. The ballast pharmaco-therapeutic action: improving functional status ischemic myocardium in MI, improves here contractile function heart, reduces the expression of systolic and diastolic dysfunction. 3 g / day), further - to 2,4 g / day (Table 4. Pharmacotherapeutic group: S05SH10 - kapilyarostabilizuyuchi means. Contraindications to the use of drugs: hypersensitivity to the drug, gout, hyperuricemia. / min drip or jet; first injected 200 mg (10 ml of 2% p-well) 1 g / day, the following terms of good portability - up Outpatient Visit 400 mg (20 ml 2% district) 1-2 g / day; rate cure - 10-15 days possible with the introduction of jet g. Pharmacotherapeutic group: A05VA50 - hepato-and cardioprotective drugs ballast . Against introduction of long-term: nausea, bloating, sleep disturbance. in / in preparation administered by drop infusion, slowly at physiological district is not, or 5% dextrose or p-(glucose) in the volume of 100 - 150 ml Keep Open Rate here - 90 min.
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