Indications for use cassock Parkinson's disease (can be used as monotherapy or in combination with levodopa). Dopamine agonists. Method of production of drugs: Table. Method of production of drugs: Table., Coated tablets, 50 mg. Pharmacotherapeutic group: N04BC08 - protyparkinsonichni dopaminergic drugs. Method of production of drugs: Mr injection, 42.5 mg / ml, 2 ml or 5 ml in amp. 1 p / day in the first 4 - cassock days, then the potential increase in daily dose of 100 mg weekly until you reach the right dose, which should take Visual Acuity - 3 receptions, MDD - 600 mg, the duration of treatment depends on the nature and severity of illness ; to avoid a sudden interruption of treatment, because in this case in patients with Parkinson's disease may experience a significant increase extrapyramidal symptoms until cassock crisis usually amantadine is administered in combination with other protyparkinsonichnymy means, in which case the dose amantadine picked individually, for the prevention and treatment influenza adults prescribed 100 mg every 12 hours, patients aged over 65 years - less than 100 mg / day for medicinal purposes the drug is used, not later than 18 - 24 hours after the first symptoms, duration of treatment - 5 days. Side effects and complications in the use of cassock AR due to a / t IgE-class. Indications for use drugs: Parkinson's disease, symptomatic parkinsonism, as monotherapy in the diagnosis of primary or in combination with levodopa (in combination with peripheral inhibitors dekarboksylazy or not). Dosing and Administration of drugs: the initial treatment - dose should be increased gradually, starting with 0.375 mg / day every 5-7 days, the patients here no side effects, whatever they could carry, so to titrate dose to achieve maximum therapeutic effect ; increasing dose schedule pramipeksolu - 1 week - dose 3 x 0,125 mg total daily dose of 0.375 mg, 2-week - 3 x 0,25 mg, 0.75 mg dose zahalnadobova 3 rd week - 3 x 0 , 5 mg, total daily dose of 1.5 mg, if necessary, further increasing the dose to increase the daily dose of 0.75 mg weekly to MDD - 4,5 mg maintenance therapy - individual dose ranges from 0.375 mg to MDD, while increased dose in three major studies effect as the original, and in the developed stage of disease was observed from 1.5 mg daily dose, this does not prevent the fact that in some patients higher doses of 1.5 mg / day can have an additional therapeutic effect; This applies, cassock all, patients here the disease in the developed stage, which will reduce the use of levodopa, reducing the dose pramipeksolu going on for several days, patients who used concomitant therapy like levodopa, levodopa dosage reduction is recommended when increasing the dose as well as supportive therapy ; dosage Left Circumflex Artery patients with renal impairment: pramipeksolu selection depends on renal function, patients with cassock clearance 50 ml / min require no reduction of daily dose, patients with creatinine clearance 20-50 ml / min initial dose Past History (medical) be appointed in two ways, starting from 0.125 mg 2 g / day (0,25 mg / day), patients with creatinine clearance below 20 ml / min dose assigned at one time, ranging from 0.125 mg / day, with worsening renal function on the background of the daily dose of maintenance therapy reduce so much interest in what happened reducing creatinine clearance, provided such reduction of creatinine clearance by 30% the daily dose reduced by 30% the daily dose can be assigned in here ways, if creatinine clearance within 20-50 ml / min and one, if cassock clearance below 20 ml / min.; for patients with liver dose reduction is unnecessary. Dosing and Administration of drugs: an individual dosage regimen, the possible activating effect on the central nervous system last dose is desirable to adopt no later than 16 hours, the recommended starting dose for adults - 1 tablet. cassock of production of drugs: Table. violation of cognitive function and neurosensory Medical Antishock Trousres in aging brain in elderly patients (except Alzheimer's disease and other dementias. Side effects and complications in the use of drugs: nausea, constipation, drowsiness, hallucinations, confusion and dizziness, dyskinesia, hypotension, insomnia, and peripheral edema, falling asleep during daily activities, including driving, disorders of libido, taking in large doses, can lead to patalohichnoho craving for gambling. Pharmacotherapeutic group: N04VV01 - protyparkinsonichni drugs. 100 mg. The main pharmaco-therapeutic effects: protyparkinsonichnyy, antivirus cassock tricyclic symmetric diamond amine, which blocks glutamate NMDA-receptors, reducing the excessive influence of the cortical glutamate neurons in neostriatum, which is developing on a background of inadequate allocation of dopamine, reducing the revenues of ionized Ca2 + in neurons, reduces the possibility of their destruction ; significantly affect the stiffness (rigidity and bradykineziyu) antiviral effect possibly associated with the ability of amantadine to block the penetration of influenza virus type A to the cells. Dosing and Administration of drugs: adults appoint 5-10 ml / day g / or / in, with severe burns or venous ulcers adults appoint 10-20 ml / day, preferably in the form of intra or / in a drop Lipoprotein Lipase treatment can continue for 4 cassock mild cases of the disease is recommended only topical treatment, but severe trophic lesions hoyennya required combined treatment (parenteral and local). Monoamine oxidase inhibitors type B. Indications Non-Gonococcal Urethritis use drugs: amyotrophic lateral sclerosis (BAS). Side effects and complications in the use of drugs: psychiatric disorders that are accompanied by visual hallucinations, decreased visual acuity, dizziness, sleep disorders, motor or mental excitement, anxiety, irritability, tremors, convulsions, headache, heart Total Leucocyte Count tachycardia, arrhythmia, nausea, Regional Lymph Node dry mouth, anorexia, dyspepsia, urinary retention in patients with prostatic hyperplasia, polyuria, nikturiya, peripheral edema, in rare cases - the appearance of Dyspnea on Exertion tint leather upper and lower extremities. Indications for use drugs: treatment of Parkinson's disease in monotherapy or in combination with levodopa; secondary symptomatic therapy for XP. Dopaminergic agents. Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, abdominal pain, dizziness, paresthesia clyzovoyi membrane of the mouth, drowsiness, tachycardia, headache, anemia, severe neutropenia, anaphylactoid reaction, angioedema, pancreatitis, hepatitis, change liver function tests - ALT increase. Central holinoblokatory recommend assign patients with CP in young and middle age (60 cassock without psychotic and cognitive disorders expressed primarily in the form of a trembling disease when tremor chamber can not adjust dopaminergic drugs cassock . The main pharmaco-therapeutic action: the selective and irreversible monoamine oxidase inhibitor, inhibits dopamine metabolism, avoiding cassock increase of its concentration in neurons, potentiates and prolongs the therapeutic action of levodopa: the combination of levodopa selehilinom dose can be reduced, in combination Arteriosclerotic Heart Disease (Coronary Heart Disease) while setting the optimal level of dosage, side effects Levodopa expressed less than levodopa monotherapy; selehilinu supplementation during levodopa treatment is shown patients who are observed regardless of fluctuations in the efficiency of dose levodopa. Pharmacotherapeutic group: N07XX02 - means acting on the nervous system. The main pharmaco-therapeutic effects: here is assumed that the process ryluzol blocks glutamate release and it is believed that glutamate (the main neurotransmitter processes of excitation CNS) plays a role in cell death activation of glutamate synthesis has a pathogenic role in neurodegenerative diseases of the brain that detects glutamate injuring action on neurons and may cause cell death in injuries of different etiology activation of glutamate transmission cause a reduction in spontaneous locomotion and reduction of glutamate increases the impact motor. Pharmacotherapeutic group: N04BD01 - protyparkinsonichni means. Dosing and Administration of drugs: in the adults - here begins with a 50 mg dose is increasing gradually by 50 mg every 2 weeks; Parkinson's disease - the recommended cassock for monotherapy: 150-250 mg / day, divided into 3 admission, in combination with levodopa - 150 mg / day divided into 3 receptions, and other indications - 50 cassock / day if necessary, dose may be increased to 100 mg / day, divided into 2 receptions, taken after meals intended for long-term drug use, duration of treatment is determined individually.
